Phenotypic heterogeneity什么意思
WebDec 18, 2013 · The selective value of phenotypic heterogeneity can be envisioned in certain cases (6, 20).Furthermore, theoretical analysis supports the view that randomly generated phenotypic diversity can increase the chances of survival when bacterial populations are subjected to rapid, severe, or complex environmental fluctuations (21, 22).Such bet … WebJan 26, 2024 · However, heterogeneity driven by contact-dependent or short-range cell–cell crosstalk cannot be evaluated with single cell transcriptomic approaches, as spatial and contextual information is lost. …
Phenotypic heterogeneity什么意思
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WebLarge heterogeneity in bleeding pattern and arthropathy is observed among patients with severe hemophilia. Studies have reported a large variability in bleedin 掌桥科研 一站式科研服务平台 WebPhenotypic heterogeneity. Phenotypic heterogeneity describes different mutations in the same gene that can sometimes give rise to strikingly different phenotypes . E.g., certain loss-of-function mutations in the RET gene, which encodes a receptor tyrosine kinase, can cause dominantly inherited failure of development of colonic ganglia, leading ...
WebPhenotypic heterogeneity in genetically identical cell populations is ubiquitous in nature (Niklas, 2014 ). This is true for most unicellular microbes, which typically never live alone. Instead, they live as communities of varying complexity, which can either be single species (“isogenic”), or multi/mixed species groups ( Ackermann, 2015 ... WebDec 23, 2024 · The logic behind the usage of phenotypic potential was that a gene with a physiological function of regulating phenotypic heterogeneity should, theoretically, have a relatively large effect on relatively more traits compared with that of other genes that only slightly affect the heterogeneity of a small number of traits as a by-product of its ...
WebJul 21, 2015 · Phenotypic heterogeneity describes the occurrence of “nonconformist” cells within an isogenic population. The nonconformists show an expression profile partially … WebFeb 15, 2024 · Phenotypic Heterogeneity in Chronic Obstructive Pulmonary Disease. Recommended Reading from the Pulmonary and Critical Care Medicine Fellowship at …
WebFeb 12, 2024 · Cell heterogeneity, such as antibiotic heteroresistance and cancer cell heterogeneity, has been increasingly observed. To probe the underlying molecular mechanisms in the dynamically changing heterogeneous cells, a high throughput platform is urgently needed to establish single cell genotype-phenotype correlations. Herein, we … eddie bauer new ceoWebSpatial heterogeneity analysis shows that these changes are mainly affected by climate zone, water-related factors (precipitation, relative humidity, soil water), and their interactive effects. Characterizing of resilience changes as reference conditions for ecosystem management and restoration has significant implications in the context of ... condolence flowers for loss of petWebApr 11, 2024 · Phenotypic heterogeneity can allow specific cells to survive sudden environmental changes that kill other members of the population. It can also lead to division of labor between individuals, which can increase the population's growth rate and facilitate the development of new biological functions (Ackermann, 2015 ; Davis & Isberg, 2016 ; … eddie bauer needlepoint christmas stockings