Bithionol uses
WebJennifer Keiser, Jürg Utzinger, in Advances in Parasitology, 2010. 8.3.2.2 Bithionol. Bithionol, a bacteriostatic agent that has been widely used as an ingredient in deodorants, shampoos and surgical soaps, has been used for treating infections with Fasciola spp. since the 1960s (Keiser and Utzinger, 2007b).Bithionol is only used in … WebAug 30, 2024 · Bithionol is used for the treatment of acute and chronic Fasciola hepatica and Paragonimus westermani. The class of the bithionol is chlorinated bis‐phenol. Bithionol is unclear and possibly an uncoupler of oxidative phosphorylation. Side effects of bithionol are nausea, diarrhea, abdominal pain, anorexia, and urticaria.
Bithionol uses
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WebBithionol was originally used as an anthelmintic. Bithionol has more recently been investigated for potential use as an anti-ovarian cancer drug and as a possible … WebBithionol is an aryl sulfide that is diphenyl sulfide in which each phenyl group is substituted at position 2 by hydroxy and at positions 3 and 5 by chlorine.A fungicide and …
Webbi·thi·o·nol. ( bī-thī'ŏ-nol ), An antiparasitic agent used for treatment of the human lungworm, Paragonimus westermani, and the Oriental liver fluke, Clonorchis sinensis; also used as … WebBithionol was given orally to hospitalized patients at the daily dose of 25 mg/kg body wt for 10 days. Three patients with acute fascioliasis received a second course of bithionol 2 …
WebOct 14, 2014 · Drug for fascioliasis • Bithionol: – Used for the treatment of fascioliasis and cerebral paragonimiasis. – Bithionol is also an alternative drug in the treatment of pulmonary paragonimiasis. – Dose: 30-50 mg/kg …
WebThe result is a simple compound that is inexpensive and easy to make in a two-step synthesis. Mouse studies by the consortium showed that when bithionol is used with the antibiotic gentamicin, the combination clears persistent MRSA infections. “Normally gentamicin doesn’t work on persister MRSA infections,” Wuest explains.
WebParagonimiasis är en livsmedelsburen parasitinfektion orsakad av lungslag , oftast Paragonimus westermani .Det berör uppskattningsvis 22 miljoner människor årligen över hela världen. Det är särskilt vanligt i Östasien .Mer än 30 arter av trematoder (flukes) av släktet Paragonimus har rapporterats; bland de mer än 10 arter som rapporterats … churchill train rideWebBithionol sulfoxide is an anti-infection agent for parasites. Bithionol sulfoxide has mutagenic activity. Bithionol sulfoxide can be used in the research of parasite infection, such as paragonimiasis, flukes andcestodes infection [1] [2] [5] . In Vitro. Bithionol sulfoxide (0.1-10 mg/mL, 72 h) shows toxicity to Neoparamoeba spp parasites in sea ... churchill transportationWebAug 5, 2024 · Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause … churchill travel insurance policyWebSep 28, 2007 · Bithionol was effective against gill monogenean parasite Microcotyle sebastis infections in marine rockfish resulting in a 66-93% reduction in parasite numbers … devonshire hotels offersWebJun 23, 1990 · The usual dosage has been 30 to 50 mg/kg daily in three divided doses on alternate days for a total of 10 to 15 doses. Lower doses have been used when this regimen is poorly tolerated. Despite its success, most series reporting bithionol therapy of F hepatica report just under 50% long term cure (14,31). An approximate 50% incidence of … devonshire hotel eastbourneWebBithionol is an antibacterial, anthelmintic, and algaecide agent. Bithionol is also a potent inhibitor of soluble adenylyl cyclase through binding to the allosteric activator site (IC 50: … churchill trapLD50 (oral, mouse) is 2100 mg/kg. Bithionol was formerly used in soaps and cosmetics until the U.S. FDA banned it for its photosensitizing effects. The compound has been known to cause photocontact sensitization. See more Bithionol is an antibacterial, anthelmintic, and algaecide. It is used to treat Anoplocephala perfoliata (tapeworms) in horses and Fasciola hepatica (liver flukes). See more Bithionol has been shown to be a potent inhibitor of soluble adenylyl cyclase, an intracellular enzyme important in the catalysis of adenosine triphosphate (ATP) to cyclic adenosine monophosphate (cAMP). Soluble adenylyl cyclase is uniquely activated by See more devonshire hotels chatsworth